What is smile line fat grafting? Is it effective and safe?
In addition to filler injections, smile line fat grafting is also a method to fill in wrinkles in the smile line area that women are interested in. So what is smile line fat grafting, does it really provide long-lasting and safe results? Let’s explore this method in detail in the following article.
1. What is smile line fat grafting?
Smile line fat grafting is a cosmetic procedure that uses the patient’s own fat, which, after being processed and selectively extracted for quality fat cells in a sterile environment, will be injected directly into the smile line area. This fills in wrinkles, reduces sagging, helps the face appear fuller and more harmonious, while also making the skin smoother and more radiant.
2. Advantages and disadvantages of smile line fat grafting
Below are the advantages and disadvantages that women need to consider before choosing the smile line fat grafting method:
2.1. Advantages
Smile line fat grafting has advantages such as:
- Safe, minimizes allergic reactions: Because it uses the patient’s own fat, this method has a low likelihood of causing allergies, no rejection reactions, or harm to health.
- High effectiveness: When grafting the essence of the patient’s own fat, the fat cells will have a high survival ratemore, bringing quick and long-lasting results.
- Non-painful, no scarring: The fat is injected into the areas that need treatment through small injection sites, so it usually does not cause pain and does not leave scars.
- Improves skin condition: In addition to filling smile lines and reducing wrinkles, autologous fat grafting also stimulates collagen and elastin production, helping the skin to be more plump and smooth.

2.2. Disadvantages
Along with the above advantages, grafting fat into smile lines also has some limitations such as:
- High cost: Grafting fat into smile lines requires a complex procedure and a doctor with solid expertise, making the cost of this service often higher than other filling methods.
- Requires recovery time: Although it does not require invasive surgery, the person undergoing the procedure still needs recovery time, especially in the early days after fat grafting.
- Risk of complications: If performed at untrustworthy addresses, this method can cause some complications such as infection, swelling, or uneven results of fat grafting in the nasolabial folds.
3. Who should and should not undergo fat grafting for nasolabial folds
Here are the people who should and should not undergo autologous fat grafting for nasolabial folds:
3.1. Suitable candidates
The autologous fat grafting method for nasolabial folds is suitable for the following individuals:
- People with deep wrinkles in the nasolabial fold area.
- People with sunken cheekbones, wanting a fuller face.
- People whose facial skin is beginning to show signs of aging, wanting to improve a more youthful appearance.
3.2. Unsuitable candidates
The fat grafting method for nasolabial folds is not suitable for individuals such as:
- Pregnant or breastfeeding women.
- People with blood clotting disorders.
- People with immune system issues or autoimmune diseases.
- Peoplesuffering from severe chronic diseases such as tuberculosis, diabetes, cardiovascular diseases, respiratory diseases.
- People with deep vein thrombosis or pulmonary embolism.

4. The fat grafting process for smile lines
The smile line fat grafting process must ensure medical standards with steps such as:
- Step 1: The doctor examines the customer’s condition while checking the area of excess fat to take autologous fat for grafting.
- Step 2: The customer will undergo tests and ultrasound to ensure health conditions are sufficient and safe for smile line fat grafting.
- Step 3: The doctor proceeds to take autologous fat from the abdomen or thigh and processes it.
- Step 4: The doctor proceeds to graft fat into the previously identified smile line area.
- Step 5: After fat grafting, the customer will rest in the post-operative room, and the doctor will provide detailed instructions on care and schedule a follow-up appointment.
5. How much does smile line fat grafting cost?
Currently, the cost of autologous fat grafting for smile lines usually ranges from 10 – 15 million VND. However, the specific price will depend on many factors such as: The condition of the smile lines of each person (shallow or deep), the amount of fat needed for grafting, the doctor’s skill, as well as the reputation and quality of the service at the cosmetic facility you choose.
6. Notes before fat grafting for smile lines
To ensure the fat grafting process for smile lines is safe and achieves the best results, you need to pay attention to the following points:
- Choose a reputable cosmetic facility licensed by the Ministry of Health, with a team of highly specialized doctors.
- Avoid using medications containing aspirin or dietary supplements that have blood-thinning effects 10 days before the procedure.
- Fully inform the doctor about your health status, medical history, and any medications you are currently taking.
- Keep a relaxed mindset and get enough sleep before the procedure date.
- Follow the detailed instructions from the doctor regarding diet and hygiene before proceeding.

7. Post-fat injection care for smile lines
Proper care after injecting fat into smile lines not only helps increase the survival rate of the fat but also ensures long-term aesthetic effectiveness. Here are some care tips you should know:
- Change the bandage and clean the fat injection area daily according to the doctor’s instructions.
- Apply cold compress for the first 24 – 48 hours to reduce swelling and pain at the injection site.
- Avoid touching, pressing, or massaging the fat injection area for at least 1 week.
- Limit lying on your side to avoid putting pressure on the fat injection area.
- Do not consume alcohol or spicy hot foods in the early stages after fat injection.
- Drink enough water, supplementEat foods rich in vitamins and protein to support recovery.
- Use medication in the correct dosage as directed by your doctor.
- Follow up regularly according to your doctor’s appointment to check the effectiveness after fat grafting.
8. How long does smile line fat grafting last?
After smile line fat grafting, the results will begin to stabilize significantly in about 3 – 4 months. The aesthetic effect from this method lasts on average from 1 – 2 years, depending on individual constitution and care methods. After this period, if you want to maintain a youthful appearance, you may consider undergoing a supplementary fat grafting procedure.

In addition to smile line fat grafting, if you have deep-set eyes, you can also apply this method to correct it. Currently, there are 2 methods of fat grafting for the eye area: upper eye fat grafting and lower eye fat grafting. Specifically, upper eye fat grafting will fill the upper eyelid, correcting the deep hollow condition and creating a fuller eye arch.and younger. Meanwhile, fat grafting under the eye socket will fill in the hollows, eliminate tear troughs, helping the eyes look less tired and aged. However, to achieve the desired and safe results, you need to perform it at a reputable cosmetic facility.
Coming to Dr. Eye – the first center in treating aging around the eyes, customers can rest assured because the fat grafting under the eye socket is performed by a team of skilled doctors, with full professional certificates and rich experience. The doctor will create a personalized treatment plan suitable for each customer, helping women effectively improve the hollow eye area and achieve a younger, fresher, and more harmonious appearance.
Not only stopping at professional competence, Dr. Eye also ensures compliance with strict medical procedures, minimizing risks and complications, bringing the safest and most effective results for customers.

Evidence of these outstanding advantages is the customers who have successfully treated the eye area at Dr. Eye, typically the case of Ms. Đào Phương Nhi. Ms. Nhi came to Dr. Eye in a state of aging around the eyes with manifestations such as hollow eye sockets, excess skin on the upper eyelids, drooping and uneven eyelid folds.
After being examined by Dr. Eye’s doctor, a treatment plan including Upper eyelid fat grafting and lower brow lift. The results after 1 month of implementation, the wound has completely healed, and Ms. Nhi’s new eyes look much younger and more radiant, so she feels extremely satisfied.

Similar to Ms. Nhi, Ms. Cam Thi Tu Quyen also once felt self-conscious about her dull eyes when she had defects such as sunken eyes, sagging excess skin, uneven eyelids, and congenital ptosis. However, after treatment with Dr. Eye according to the protocol of Upper eyelid surgery – Ptosis treatment – Autologous fat grafting, the previous defects have significantly improved, and Ms. Quyen’s eyes now look more vibrant and attractive.

In addition, sisters can also see more reviews from other customers about the doctor’s skills and service quality at Dr. Eye such as:



What are you waiting for contact Dr. Eye now to have a beauty expert examine and advise on a suitable treatment plan, helping sisters ‘erase’ the traces of time effectively and safely!
In summary, fat grafting for smile lines will bring noticeable results in filling wrinkles and helping you look younger. However, to ensure safety and long-lasting effectiveness, you need to perform it at reputable facilities to be examined and performed by specialized doctors.
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References
- Facial Fat Grafting. https://med.stanford.edu/cosmeticsurgery/aestheticservices/face/facial-fat-grafting.html (accessed 01/10/2025)
- What to Know About Fat Grafting for Facial Rejuvenation. 11/10/2023. https://ohns.ucsf.edu/facialplastics/what-know-about-fat-grafting-facial-rejuvenation (accessed 01/10/2025)
- Dr. Lubitz. The Pros and Cons of Fat Transfer. https://www.artofskin.ca/2018/08/08/the-pros-and-cons-of-fat-transfer/ (accessed 01/10/2025)
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Understanding the desire to preserve the youthful beauty of the eyes for middle-aged women, Dr. Eye offers modern solutions to address all aging issues around the eyes such as sagging eyelids, eye bags, crow’s feet,…












